An EXCEL template for calculation of enzyme kinetic parameters by non- linear regression

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An EXCEL template for calculation of enzyme kinetic parameters by non-linear regression

MOTIVATION An EXCEL template has been developed for the calculation of enzyme kinetic parameters by non-linear regression techniques. The tool is accurate, inexpensive, as well as easy to use and modify. AVAILABILITY The program is available from http://www.ebi.ac.uk/biocat/biocat.html CONTACT agustin. [email protected]

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Statistical considerations in the estimation of enzyme kinetic parameters by the direct linear plot andother methods.

The statistical implications of the direct linear plot for enzyme kinetic data, described in the preceding paper (Eisenthal & Cornish-Bowden, 1974), are discussed for the case of the Michaelis-Menten equation. The plot is shown to lead directly to non-parametric confidence limits for the kinetic parameters, V and K(m), which depend on far less sweeping assumptions about the nature of experiment...

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ESTIMATING THE PARAMETERS OF A FUZZY LINEAR REGRESSION MODEL

Fuzzy linear regression models are used to obtain an appropriate linear relation between a dependent variable and several independent variables in a fuzzy environment. Several methods for evaluating fuzzy coefficients in linear regression models have been proposed. The first attempts at estimating the parameters of a fuzzy regression model used mathematical programming methods. In this the...

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ژورنال

عنوان ژورنال: Bioinformatics

سال: 1998

ISSN: 1367-4803,1460-2059

DOI: 10.1093/bioinformatics/14.2.227